TreesimJ is a flexible, individual-based population genetic simulator. It tracks the state of a population evolving in forward time via discrete, Wright-Fisher generations. It also maintains the full genealogical tree of the population and allows for collecting sample trees which can be analyzed, exported and logged. It can also simulate evolving DNA under a variety of assumptions regarding mutation and selection. TreesimJ is very flexible, meaning that a wide variety of fitness models, demographic models, and data collectors are supported, and new models are easy to write. The application also sports an intuitive graphical interface, so users unfamiliar with the command line or XML can easily use the program to generate and analyze genetic data. It was recently published in the journal Bioinformatics.

TreesimJ can now handle some simple models of population structure. Currently there are two models implemented - the island model, in which populations of equal and constant size exchange migrants, and a "Population Split" model, in which an ancestral population splits into two descendant populations which may be connected via migration. A stepping-stone model is in the works.

Requirements:
* Java

The license of this software is Freeware, you can free download and free use this calculator software.