Automation of the PSI-BLAST results analysis. Summarize PSI-BLAST iteration results with this tool. PSI Protein Classifier is a new program that allows to summarize the consecutive and independent PSI-BLAST iteration results. The technical opportunities of the program are explained. Two examples of the PSI Protein Classifier application are given. Iterative screening of the protein database allowed to reveal feasible evolutionary relationship among GH5, GH13, GH27, GH31, GH36, GH66, and GH101 families of glycoside hydrolases. Family GH31 is divided into 38 subfamilies on the basis of statistically significant sequence similarity analysis (E-value analysis).

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