Molecule analysis made easy. FTrees has been reported to be highly successful in numerous projects by various customers in
1. lead finding,
2. HTS analysis, and
3. general virtual screening applications.

FTrees is a piece of program for calculating the Feature Tree descriptor and comparing two or more of these descriptors to each other. The capability to detect novel molecular scaffolds is one of several features that charaterizes FTrees abilities.

Molecular similarity is one of the major concepts in the design of new drugs. This is especially the case if no three-dimensional structure of the target protein is available. It is then necessary to search for new lead structures via screening or to derive them from known inhibitors or natural substrates.

FTrees Features:
1. Wizards to guide users through the most crucial steps of molecule conversion, comparison and clustering
2. A new introduction to FTrees in the form of a tutorial - in fact in you are new to FTrees, finish reading this section and make a start there!
3. New comparison algorithm Dynamic Match-Search including subgraph matching feature
4. Conformation independent molecule handling giving full SMILES and SD format support
5. User accessible molecule preparation tools managed via SMARTSTM
6. Stablized windows version plus an installer script
7. Output of molecule-based alignment information
8. Similarity threshold filtering of results
9. Hierarchical clustering module
10. Increased in-memory Feature Tree capacity and large file support

The license of this software is Freeware, you can free download and free use this calculator software.